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By L. Silas. Framingham State College.

This section ends with an essay that locates the previous discussions in terms of the challenge of bringing bioethics to speak to the pressing issues of normative ethics: “Bioethics at Century’s Turn: Can Normative Ethics Be Retrieved? The default position in bioethics and health care policy tends to be procedural rather than substantive cheap noroxin 400 mg fast delivery virus 68 michigan, because substance divides and en- © 2008 University of Notre Dame Press An Introduction genders dispute. Quoting Gilbert Meilaender, Pellegrino concludes that bioethics has “lost its soul. The last subsection is a brace of papers exploring the Hippocratic tra- dition and its capacity to inform a bioethics for the future. The frst essay, “Toward an Expanded Medical Ethics: The Hippocratic Ethic Revisited,” begins by recognizing that “Good physicians are by the nature of their vocation called upon to practice their art within a framework of high moral sensitivity. For two millennia this sensitivity was provided by the oath and the other ethical writings of the Hippocratic corpus. No code has been more infuential in heightening the moral refexes of ordinary indi- viduals. Every subsequent medical code is essentially a footnote to the Hippocratic precepts, which even to this day remain the paradigm of how good physicians should behave. This Hippocratic ideal he shows to lie at the heart of the Hippocratic com- mitment to protecting the vulnerability of the patient. Pellegrino then ex- amines the shortcomings of the Hippocratic Oath and its ethos in the service of pointing to the possibility of “the elaboration of a fuller and more comprehensive medical ethic suited to our profession as it nears the twenty-frst century. Through a study directed primarily to the Oath, Pellegrino dis- plays its limitations, while yet recognizing its importance for the history of medical ethics. As he appreciates, the Hippocratic tradition, despite its past infuence, must be reappropriated through a moral philosophy of medicine that takes account of “the moral heterogeneity of modern societies and the cosmopolitan character of scientifc medicine. That is, Pellegrino argues that medicine’s internal morality must be understood through a moral philosophy internal to medicine and prior to medical ethics. Only such a moral philosophy of medicine, when adequately de- veloped, so Pellegrino claims, will be able to meet the challenges of the fu- ture. Pellegrino and the Future This volume both refects a cultural crisis or rupture and indicates possible responses to the challenges this brings. This collection of essays recognizes medicine’s break from its sense of possessing tradition, a sense of continuity repeatedly re-achieved over the centuries by means of an af- frmation of that period’s understanding of the Hippocratic ethos. Pel- legrino attempts to fnd a surrogate ethos and sense of professionalism in the face of rapid cultural change by reaching to the humanities and a phil- osophically recast bioethics. These essays of Pellegrino show a deep ap- preciation for the search for orientation in the face of post-modernity’s cacophony and the constant presence of the moral concerns integral to the physician-patient relationship. It recognizes as well that bioethics at- tempted to claim hegemony over medical ethics, though bioethics itself failed to realize a unifed normative undertaking. Though bioethics arose to give guidance in a cultural vacuum consequent upon the secularization of American society and the marginalization of the traditional authority of physicians, bioethics has nevertheless failed to provide, much less jus- tify, a canonical moral perspective that can supply the guidance sought. Again, he locates bioethics within a vision of the human enterprise, a core contribution of the humanities. He then places all of this within a philosophy of medicine that takes seriously that which is essen- tial to the calling of physicians. It ofers an interesting proposal for rethinking the nature of the philosophy of medicine and its ofce in grounding and directing not just the medical humanities and bioethics, but medical eth- ics and medical professionalism. Pellegrino has shaped the development of the philosophy of medi- cine, the medical humanities, bioethics, and medical ethics. The past would not have been the same in the absence of his scholarship and per- sonal engagement. His scholarship reaches to the future and to the pos- sibility of recapturing an authentic medical ethics, an ethics for the medical profession. Pellegrino’s work ofers a basis for approaching bioethics and the medical humanities afresh. By addressing core but underexamined is- sues in the philosophy of medicine, he indicates an avenue toward recov- ering a sense of commitment to virtue and service on the part of the medical profession. By recognizing the physician-patient relationship as the central, moral-epistemic context for medical ethics, he provides a teleological account of the practice of medicine in terms of its pursuit of the medical good of the patient. The project he has begun promises a deeper understanding of medicine, as well as an opportunity for recaptur- ing a moral sense of medical-professional identity.

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When more advanced personnel arrive on scene cheap 400 mg noroxin visa generic antibiotics for acne, it is the team leader who communicates with advanced personnel, providing them with a report of the patient’s status and events. The team leader also sets clear expectations, prioritizes, directs, acts decisively, encourages team input and interaction and focuses on the big picture. Crew Resource Management During resuscitation, crew resource management helps to promote effective and efficient teamwork. Crew resource management is a communication process that centers around the team leader, who coordinates the actions and activities of team members so that the team functions effectively and efficiently. For example, when new individuals arrive on the scene or when team members switch roles during an emergency, it is the team leader who is responsible for coordinating these activities. Crew resource management also guides team members to directly and effectively communicate to a team leader about dangerous or time-critical decisions. It was developed as a result of several airline disasters as a way to prevent future incidents. Crew resource management has been shown to help avoid medical errors in healthcare. To effectively communicate via crew resource management, team members should get the attention of the team leader, and state their concern, the problem as they see it and a solution. Working together, the team should then be sure to obtain direction from the team leader. Basic Life Support for Healthcare Providers Handbook 25 Pediatric Considerations Children are not small adults. In most instances, determining whether to treat a child as a child or as an adult has been based on age. However, for the purposes of this course, a child is defined as the age of 1 to the onset of puberty as evidenced by breast development in girls and underarm hair development in boys. Consent Another factor to consider when caring for children and infants is consent. Legally, adults who are awake and alert can consent to treatment; if they are not alert, consent is implied. However, for most infants and children up to the age of 17 years, you must obtain consent from the child’s parent or legal guardian if they are present regardless of the child’s level of consciousness. To gain consent, state who you are, what you observe and what you plan to do when asking a parent or legal guardian permission to care for their child. If no parent or legal guardian is present, consent is implied in life-threatening situations. Always follow your local laws and regulations as they relate to the care of minors. Science Note Most child-related cardiac arrests occur as a result of a hypoxic event such as an exacerbation of asthma, an airway obstruction or a drowning. As such, ventilations and appropriate oxygenation are important for a successful resuscitation. In these situations, laryngeal spasm may occur, making passive ventilation during chest compressions minimal or nonexistent. Airway To open the airway of a child, you would use the same head-tilt/chin-lift technique as an adult. However, you would only tilt the head slightly past a neutral position, avoiding any hyperextension or flexion in the neck. Basic Life Support for Healthcare Providers Handbook 27 Table 1-2 Airway and Ventilation Differences: Adult and Child Child (Age 1 Through Adult Onset of Puberty) Airway Head-Tilt/Chin-Lift Past neutral position Slightly past neutral position Ventilations Respiratory Arrest 1 ventilation every 5 to 1 ventilation every 3 seconds 6 seconds 28 American Red Cross Compressions The positioning and manner of providing compressions to a child are also very similar to an adult. Place your hands in the center of the chest on the lower half of the sternum and compress at a rate between 100 to 120 per minute. Compressions-to-Ventilations Ratio When you are the only rescuer, the ratio of compressions to ventilations for a child is the same as for an adult, that is, 30 compressions to 2 ventilations (30:2). However, in two-rescuer situations, this ratio changes to 15 compressions to 2 ventilations (15:2).

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It is important therefore that pupils and staff who are ill when they come to school trusted noroxin 400mg infection heart rate, or who develop symptoms during the school day, should be sent home. Whenever possible, ill pupils should be removed from the classroom while waiting to go home. Obvious symptoms of illness are diarrhoea, vomiting, fever, cough, sore throat and rash. For most illnesses, pupils and staff may return to school once they feel well enough to do so. In some instances however, it may be necessary to exclude pupils and staff from school for specifed periods to prevent the spread of infection. Implementation of Standard Precautions and basic good hygiene practices Placing reliance on the identifcation of all potentially infectious individuals and their exclusion from schools will not effectively control the spread of infection in schools, which is why standard precautions and good hygiene practices are also recommended. Standard precautions are work practices that were designed based on the assumption that all blood and all body fuids are potentially infectious. These precautions are recommended to prevent disease transmission in schools and should be adopted for contact with all blood and body fuids. Hand washing Hand washing is the single most effective way to prevent the spread of infection; its purpose is to remove or destroy germs that are picked up on the hands. Germs can be picked up in lots of ways including when we touch other people, animals, contaminated surfaces, food and body fuids. These germs can then enter our body and make us ill or they can be passed to other people or to the things that we touch. Germs picked up on the hands can be effectively removed by thorough hand washing with soap and running water. Pupils of all ages should be encouraged to wash their hands and school staff should avail of every opportunity to emphasise the importance of clean hands to pupils in the prevention of the spread of infection. Hand washing facilities Good toilet and hand washing facilities are important for infection control. Cleaning staff should be reminded to check the soap dispensers at frequent intervals. When to wash hands Before • Handling or preparing food • Lunch and meal breaks • Providing frst aid or medication After • Providing frst aid or medication • Touching blood or body fuids • Using the toilet • Coughing, sneezing or wiping ones nose • Touching animals • Removing protective gloves See Appendix 2, 3, 4 and 5 for posters on hand washing Hand washing products • Liquid soap and warm running water should be provided. Bar soap is not recommended as the soap can easily become contaminated with bacteria. Water temperature • Ideally, wash hand basins should have hot and cold mixer taps that are thermostatically controlled to deliver hot water at a maximum temperature of 43◦C to avoid scalding. If the plumbing system only supplies cold water, a soap that emulsifes easily in cold water should be provided. Include the thumbs, fnger tips, palms and in between the fngers, rubbing backwards and forwards at every stroke (see Posters on hand washing technique in the Appendices). Drying • Good quality disposable paper towels (preferably wall mounted) should be available at or near the wash hand basins for drying hands. Alcohol based hand rubs/gels Alcohol based hand rubs/gels are not a substitute for hand washing with soap and running water and are not generally recommended for routine use in educational settings because of concerns over safety, and the fact that the rubs/gels are not effective when used on hands that are visibly dirty (a common feature among school children). Alcohol-based hand rubs and gels are a good alternative when soap and running water are not available, (e. Method • Apply the required volume of the product to the palm of one hand and rub the hands together. The amount of gel used should be enough to keep the hands wet for at least 15 seconds. Health and Safety As with any other household product or chemical, alcohol hand rubs can be hazardous if used inappropriately. If alcohol hand rubs/gels are used in the school setting, care should be taken to ensure that children do not accidentally ingest hand washing products. Hand washing and young children Good hand washing habits should be taught to young pupils as early as possible. This can be done by: • Showing children a good hand washing technique (See posters on hand washing in Appendices). Gloves Disposable gloves should be worn when dealing with blood, body fuids, broken or grazed skin, and contact with mucous membranes (e. Medical/examination gloves • Disposable, powder free gloves made of either natural rubber latex or nitrile are suitable for use in these circumstances as they have good barrier properties. Medical/examination gloves are recommended for: • Dealing with nosebleeds or cuts.

Amylase digestion produces large oligosaccharides (α-limit dextrins) that contain approximately eight glucose units of one or more α-(1 purchase noroxin 400mg with amex virus not alive,6) linkages. The microvilli of the small intestine extend into an unstirred water layer phase of the intestinal lumen. When a limit dextrin, trisaccharide, or disaccharide enters the unstirred water layer, it is rapidly hydrolyzed by enzymes bound to the brush border membrane. These limit dextrins, produced from starch digestion, are degraded by glucoamylase, which removes glucose units from the nonreducing end to yield maltose and isomaltose. Maltose and isomaltose are degraded by intestinal brush border disaccharidases (e. Maltase, sucrase, and lactase digest sucrose and lactose to monosaccharides prior to absorption. Intestinal Absorption Monosaccharides first diffuse across to the enterocyte surface, followed by movement across the brush border membrane by one of two mecha- nisms: active transport or facilitated diffusion. The intestine is one of two organs that vectorially transports hexoses across the cell into the bloodstream. The mature enterocytes capture the hexoses directly ingested from food or produced from the digestion of di- and polysaccharides. The resultant gradient results in the cotransport of one molecule each of sodium and glucose. The driving force for glucose transport is the glucose gradient and the energy change that occurs when the unstirred water layer is replaced with glucose. In this type of transport, called facili- tated diffusion, glucose is transported down its concentration gradient (from high to low). Absorbed sugars are transported throughout the body to cells as a source of energy. The concentration of glucose in the blood is highly regulated by the release of insulin. Most of the glucose-1-phosphate derived from galactose metabolism is converted to glycogen for storage. The glyceraldehyde can be con- verted to glycolytic intermediary metabolites that serve as precursors for glycogen synthesis. Glyceraldehyde can also be used for triacylglycerol synthesis, provided that sufficient amounts of malonyl coenzyme A (CoA) (a precursor for fatty acid synthesis) are available. In muscle, glucose is metabolized anaerobically to lactate via the glycolytic pathway. After the consumption of carbohydrates, fat oxida- tion is markedly curtailed, allowing glucose oxidation to provide most of the body’s energy needs. In this manner, the body’s glucose and glycogen content can be reduced toward more normal concentrations. Glucose can be synthesized via gluconeogenesis, a metabolic pathway that requires energy. Gluconeogenesis in the liver and renal cortex is inhibited via insulin following the consumption of carbohy- drates and is activated during fasting, allowing the liver to continue to release glucose to maintain adequate blood glucose concentrations. Glucose can also be converted to glycogen (glycogenesis), which contains α-(1-4) and α-(1-6) linkages of glucose units. Glycogen is present in the muscle for storage and utilization and in the liver for storage, export, and maintenance of blood glucose concentrations. Glycogenesis is activated in skeletal muscle by a rise in insulin concentration following the consumption of carbohydrate. In the liver, glycogenesis is activated directly by an increase in circulating glucose, fructose, galactose, or insulin concentration. Following glycogenolysis, glucose can be exported from the liver for maintenance of normal blood glucose concentrations and for use by other tissues. A limited amount of carbohydrate is converted to fat because de novo lipogenesis is generally quite minimal (Hellerstein, 1999; Parks and Hellerstein, 2000).

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